Aseptic Processing & Containment Solutions

Aseptic processing and containment systems provide controlled, sterile, or high-containment environments for fill-finish, assembly, and hazardous material handling in pharmaceutical and biotech production. Through an exclusive U.S. distribution partnership with Ravona, TurboFil offers a full suite of isolators, Restricted Access Barrier Systems (RABS), glove integrity testers, and integrated fill-finish + containment solutions.

These systems support manufacturers needing regulatory-grade environments — whether for aseptic fill-finish, handling of high-potency active pharmaceutical ingredients (HPAPIs), or compliance with cleanroom standards such as Annex 1 and OEB 4-6.

Aseptic Processing & Containment Solutions

  • RABS

  • Isolators

  • Glove Integrity Testers

Overview of Aseptic & Containment Technologies

TurboFil’s aseptic offerings through Ravona include both standalone containment technologies and fully integrated solutions that combine barrier systems with automated fill-finish equipment.

  • Isolators: Fully sealed barrier environments that maintain sterile (positive-pressure) or high-containment (negative-pressure) conditions for critical processes.

  • RABS (Restricted Access Barrier Systems): Controlled Grade A environments with flexible access and lower life-cycle cost than traditional cleanroom enclosures.

  • Glove Integrity Testers: Automated systems for routine verification of glove barrier integrity in isolators and RABS systems.

Each solution can be configured to match specific process requirements, facility layouts, and regulatory compliance goals.

When to Choose Aseptic & Containment Solutions

Aseptic processing and containment systems are selected when environmental control is critical to product sterility, operator safety, or regulatory compliance. They are often deployed in pharmaceutical fill-finish operations, handling of HPAPIs, or any process requiring Grade A or equivalent clean environments.

Standalone systems are often used where local containment or sterile access is needed without a full cleanroom retrofit. Integrated systems pair containment with filling and assembly machines for turnkey fill-finish solutions.

Aseptic Processing & Containment FAQs

An isolator provides a fully sealed barrier for the most stringent containment or aseptic environments, often achieving cleanroom-equivalent conditions. A RABS uses a physical barrier with controlled airflow to offer a Grade A environment with more flexible operator access.

Depending on application needs, aseptic and containment systems can be configured to support:

  • Fill-finish of sterile injectables

  • Injectable drug assembly and packaging

  • Handling of HPAPIs or cytotoxic compounds

Barrier systems are designed to help manufacturers meet regulatory and quality standards for sterile processing, including Annex 1 and ISO cleanroom classifications.

Glove integrity testers ensure isolator and RABS glove barriers are leak-free before use. Available options include portable testers, multi-tester trolleys, and integrated glove testing modules that support compliance and reduce contamination risk.

Choosing a solution depends on process requirements, desired cleanroom class, containment level (sterility vs HPAPI protection), facility layout, and integration needs. Consulting with applications engineers is recommended to match system capabilities to specific regulatory and production demands.

Standalone containment systems are ideal when existing equipment must operate in a controlled environment without line replacement. Integrated systems are best when building or upgrading a production line requiring both precision equipment and barrier environments from the start.

Plan Your Aseptic Processing or Containment Solution